Human Insulin Receptor antibody 83-14 is a murine monoclonal antibody (IgG2a) that recognizes an epitope within amino acids 469-592 of the extracellular domain of the human insulin receptor. The antibody strongly inhibits the binding of 125I-insulin binding to the insulin receptor of HIR3.5/3T3 cells.
References:
Ward C.W. (1999) J. Struct. Biol. 125, 11-18
Source:
Murine monoclonal antibody
Immunogen:
Transfected 3T3 cells overexpressing the human Insulin Receptor
State and Appearance:
Lyophilized powder
Specificity:
Does not cross-react with the rat Insulin Receptor or the human Type 1 IGF Receptor. Biological Activity:
The antibody strongly inhibits insulin binding to the Insulin Receptor of 3T3 cells.
Storage/Stability:
At least 2 years at 2 - 4°C (lyophilized)
After reconstitution store at -20°C or -80°C
Avoid freeze-thaw cycles
Reconstitution:
Dissolve in 200 µl phosphate buffered saline pH7.4
